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This document, to be used together with ISO 4254-1, specifies the safety requirements and their verification for the design and construction of mounted, semi-mounted, trailed and self-propelled agricultural sprayers for use with plant protection products (PPP) and liquid fertilizer application, as placed on the market by the manufacturer and designed for a single operator only. In addition, it specifies the type of information on safe working practices (including residual risks) to be provided by the manufacturer. When requirements of this document are different from those which are stated in ISO 4254-1, the requirements of this document take precedence over the requirements of ISO 4254-1 for machines that have been designed and built according to the provisions of this document. This document, taken together with ISO 4254-1, deals with significant hazards, hazardous situations and events relevant to sprayers and liquid fertilizer distributors when they are used as intended and under the conditions foreseeable by the manufacturer (see Annex A), excepting the hazards arising from: — protection of the driver against spray when spraying (see Foreword); — automatically actuated height adjustment systems; — the environment, other than noise; — moving parts for power transmission except strength requirements for guards and barriers. This document is not applicable to sprayers and liquid fertilizer distributors which are manufactured before the date of publication of this document.