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This document specifies only the requirements for a product assembled from the in-series combination of safety valves or CSPRS (controlled safety pressure relief systems) according to ISO 4126-1, ISO 4126-4 and ISO 4126-5, and bursting disc safety devices, according to ISO 4126-2, installed upstream of the valve within five pipe diameters of the valve inlet. It specifies the design, application and marking requirements for such products, composed of the bursting disc safety device, a safety valve or CSPRS and, where applicable, a connecting pipe or spool piece. In addition, it gives a method for establishing the combination discharge factor used in sizing combinations.