ISO-23921 › Cigarettes - Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime - Method using LC-MS/MS

ISO-23921 - 1ST EDITION - CURRENT


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This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of cigarette mainstream smoke with the intense smoking regime specified in ISO 20778 by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

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65.160 (Tobacco, tobacco products and related equipment)

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Document Number

ISO 23921:2020

Revision Level

1ST EDITION

Status

Current

Publication Date

Sept. 1, 2020

Committee Number

ISO/TC 126