ISO-21766 › Tobacco and tobacco products - Determination of tobacco-specific nitrosamines in tobacco products - Method using LC-MS/MS

ISO-21766 - 2ND EDITION - CURRENT
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This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in tobacco and the following tobacco products: cigarettes, cigars and smokeless tobacco products using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The TSNAs determined with this method are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

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Document Number

ISO 21766:2021

Revision Level

2ND EDITION

Status

Current

Publication Date

Feb. 1, 2021

Committee Number

ISO/TC 126